My last post was a nerdy list of pathogenetic mechanisms in PSP along with the statement that treatments to address most of those mechanisms are in the clinical pipeline. One of you wrote in to kick me out of my lofty, scientific detachment, asking just what those treatment candidates are. So here’s a list.

The first four panels are active trials and the last is future trials.

The first two and last panels show neuroprotection trials (i.e., to slow disease progression).

The third and fourth show symptomatic trials (i.e., to help the symptoms without affecting the underlying disease process).

For current information on how to enroll, visit clinicaltrials.gov and search on the drug and/or sponsor and/or “progressive supranuclear palsy.”